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Edijs Vavers Selected Research

4-amino-3-phenylbutyric acid (phenibut)

9/2020Safety and Tolerability of the Anxiolytic and Nootropic Drug Phenibut: A Systematic Review of Clinical Trials and Case Reports.
1/2020Mitochondrial-Protective Effects of R-Phenibut after Experimental Traumatic Brain Injury.
11/2016The neuroprotective effects of R-phenibut after focal cerebral ischemia.
10/2015R-phenibut binds to the α2-δ subunit of voltage-dependent calcium channels and exerts gabapentin-like anti-nociceptive effects.

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Edijs Vavers Research Topics

Disease

3Seizures (Absence Seizure)
01/2021 - 10/2015
2Traumatic Brain Injuries (Traumatic Brain Injury)
10/2021 - 01/2020
2Hypoxia (Hypoxemia)
11/2020 - 01/2020
2Brain Ischemia (Cerebral Ischemia)
11/2016 - 09/2011
2Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
11/2016 - 09/2011
1Adenocarcinoma
01/2022
1Neurodegenerative Diseases (Neurodegenerative Disease)
10/2021
1Necrosis
10/2020
1Substance-Related Disorders (Drug Abuse)
09/2020
1Sleepiness
09/2020
1Schizophrenia (Dementia Praecox)
12/2019
1Cognitive Dysfunction
10/2019
1Obesity
01/2017
1Body Weight (Weight, Body)
01/2017
1Hyperglycemia
01/2017
1Nervous System Diseases (Neurological Disorders)
01/2017
1Weight Gain
01/2017
1Metabolic Syndrome (Dysmetabolic Syndrome X)
01/2017
1Stroke (Strokes)
11/2016
1Neuralgia (Stump Neuralgia)
10/2015
1Hyperalgesia
10/2015
1Ischemia
06/2013
1Type 2 Diabetes Mellitus (MODY)
05/2012
1Diabetes Complications
05/2012
1Infarction (Infarctions)
09/2011

Drug/Important Bio-Agent (IBA)

44-amino-3-phenylbutyric acid (phenibut)IBA
09/2020 - 10/2015
3Proteins (Proteins, Gene)FDA Link
01/2022 - 01/2017
2Neuroprotective AgentsIBA
10/2021 - 11/2016
2LigandsIBA
10/2021 - 01/2017
2Sigma-1 ReceptorIBA
10/2021 - 01/2017
2Pentylenetetrazole (Metrazol)IBA
01/2021 - 10/2015
2imidazole mustard (BIC)IBA
01/2021 - 01/2017
2Dizocilpine Maleate (Dizocilpine)IBA
12/2019 - 10/2019
2Carnitine (L-Carnitine)FDA LinkGeneric
06/2013 - 05/2012
1BicucullineIBA
01/2021
1GABA-B ReceptorsIBA
01/2021
1Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone (FCCP)IBA
11/2020
1Glutamic Acid (Glutamate)FDA Link
11/2020
1Interleukin-1beta (Interleukin 1 beta)IBA
10/2020
1Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
10/2020
1CalciumIBA
01/2020
1N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
12/2019
12- (4- morpholino)ethyl- 1- phenylcyclohexane- 1- carboxylateIBA
01/2017
1N,N- dipropyl- 2- (4- methoxy- 3- (2- phenylethoxy)phenyl)ethylamine monohydrochlorideIBA
01/2017
1Appetite Depressants (Anorectics)IBA
01/2017
1Blood Glucose (Blood Sugar)IBA
01/2017
1Glucose (Dextrose)FDA LinkGeneric
01/2017
1S-phenylpiracetamIBA
01/2017
1LeptinIBA
01/2017
1Carnitine O-Palmitoyltransferase (Carnitine Palmitoyltransferase II)IBA
06/2013
12- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA
06/2013
1Fatty Acids (Saturated Fatty Acids)IBA
06/2013
13-(2,2,2-trimethylhydrazine)propionateIBA
09/2011